TEST SERIES CSIR NET (LIfe Science) Unit 2 B

Based on Unit 2 (B)

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• This Quiz has 20 MCQ 
• All Questions carries 1 markes each.
•  No Negative Marking
• Students can find quiz response on their mail id.

Write back for any inquiry / suggestions

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Bioscience MCQs

Introduction to Bioscience MCQs

This MCQs contains 20 questions each question carries 1 mark 

NO NEGATIVE MARKING

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For all Engineering and Science Students Studying Bioscience 

Attempt this quiz before 30th November 2013..

Find the results and correct answers of this quiz on your mail id. 

Good Luck

ARVIND ARYA 

to get updated study material, and videos follow this blog...http://catechize20.blogspot.in

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Mitochondrial Diseases their Types, Diagnosis & Treatment (In Pictures)

Mitochondrial Diseases their Types, Diagnosis & Treatment (In Pictures)

Mitochondrial disease is a group of disorders caused by dysfunctional mitochondria, the organelles that generate energy for the cell. Mitochondria are found in every cell of the human body except red blood cells. Mitochondria convert the energy of food molecules into the ATP that powers most cell functions.

Mitochondrial diseases are sometimes (about 15% of the time) caused by the mitochondrial DNA that affect mitochondrial function. Mitochondrial diseases take on unique characteristics both because of the way the diseases are often inherited and because mitochondria are so critical to cell function. The subclass of these diseases that have neuromuscular disease symptoms are often called a mitochondrial myopathy.

Examples of Mitochorndrial Diseases

Diabetes mellitus and deafness (DAD)

·         This combination at an early age can be due to mitochondrial disease

·         Diabetes mellitus and deafness can also be found together for other reasons

Leber's hereditary optic neuropathy (LHON)

·         visual loss beginning in young adulthood

·         eye disorder characterized by progressive loss of central vision due to degeneration of the optic nerves and retina

Wolff-Parkinson-White syndrome

·         Multiple sclerosis-type disease

·         Affects 1 in 50,000 people in Finland

Leigh syndrome, subacute sclerosing encephalopathy

·         After normal development the disease usually begins late in the first year of life, although onset may occur in adulthood

·         A rapid decline in function occurs and is marked by seizures, altered states of consciousness, dementia, ventilatory failure

Neuropathy, ataxia, retinitis pigmentosa, and ptosis (NARP)

·         progressive symptoms as described in the acronym

·         dementia

Myoneurogenic gastrointestinal encephalopathy (MNGIE)

·         Gastrointestinal pseudo-obstruction

·         Neuropathy

Myoclonic Epilepsy with Ragged Red Fibers (MERRF)

·         Progressive myoclonic epilepsy

·         "Ragged Red Fibers" – clumps of diseased mitochondria accumulate in the subsarcolemmal region of the muscle fiber and appear as "Ragged Red Fibers" when muscle is stained with modified Gömöri trichrome stain

·         Short stature

·         Hearing loss

·         Lactic acidosis

·         exercise intolerance

Mitochondrial myopathy, encephalomyopathy, lactic acidosis, stroke-like symptoms (MELAS)

·         mtDNA depletion

·         mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)

Further Readings:

• Types of Mitochondrial Disease// (United Mitochondrial Disease Foundation)
• Mitochondrial Disease // medicinenet.com
• http://vimeo.com/62446736
• mtDNA and Mitochondrial Diseases

List of Revolutions in the field of Agriculture in India

List of Revolutions in the field of Agriculture in India

·         Black Revolution – Petroleum Production

·         Blue Revolution – Fish Production [Further Readings 1, 2]

·         Brown Revolution – Leather/non-conventional(India)/Cocoa production

·         Golden Fibre Revolution – Jute Production

·         Golden Revolution – Fruits/Overall Horticulture development/Honey Production

·         Green Revolution – Food grains [Further Readings 1, 2, 3]

·         Grey Revolution – Fertilizer

·         Pink Revolution – Onion production/Pharmaceutical(India)/Prawn production

·         Red Revolution – Meat and Tomato Production

·         Round Revolution – Potato

·         Silver Fiber Revolution – Cotton

·         Silver Revolution – Egg/Poultry Production

·         White Revolution (In India: Operation Flood) – Milk/Dairy production

·         Yellow Revolution – Oil Seeds production

·         Evergreen Revolution – Overall development of Agriculture

Read the Article on ICAR

CSIR NET JRF (LIFE SCIENCE) Unit I (Second Quiz)

CSIR NET JRF (LIFE SCIENCE) MCQ

BASED ON UNIT I 
Second Quiz

click here to start the quiz

Instructions: 

• This quiz has 20 MCQs based on Unit I of CSIR NET LIFE SCIENCE. 
• Each Question carries 1 marks,, No Negative Marking.
• You can find the quiz response on your mail id.
• Comment below or Write me at arvindarya@hotmail.com, catechize20@gmail.com to get the complete explanation of each question of the quiz..

.....Visit blog to find more online Quizzes ..... 

Arvind Arya 

Introduction to Biosciences Notes and Videos

Compiled Notes of Introduction to Bioscience (AS 104/AS 204) for Engineering students 

**Syllabus**

• learners can find a number of Questions and Answers in these notes 
• Students are requested to use these notes as supplementary study material only. Consult your Course instructor for further details or refer the text books. 

Text books:

1. “Concepts in Biology” by Elden D Enger, Frederick C Ross and David B Bailey: TataMcGraw Hill Education Private Limited, New Delhi
2. “Biology” Text Book for Class XII by National Council of Educational Research and Training, New Delhi

 Reference Material:

• http://www.mhhe.com/enger14e
• http://www.biotech.ca/EN/history.html
• http://statwww.berkely.eu/users/terry/classes/s2601998/week8b/week8b/nod9.html
• Amgen 2004 About Biotechnology. http://amgen.com/rnd/biotechnology.html

• for any further queries or suggestions.... comment below or mail me:  arvindarya@hotmail.com

Download link Unit I ....Click here

Download link Unit II ....Click here

Download link Unit III ....Click here // Supplementry Study material //
Download link Unit IV....Click here
Download link Unit V....Click here LINK 1, LINK 2

Click on the images below to watch the animations 

DNA Fingerprinting

Cell division Animation 1

Cell division Animation 2

watch the videos below on important topics 

Human Reproduction (Female Reproductive System)

Human Reproduction (Fertilization)

Human Reproduction (Oogenesis)

Human Reproduction (Menstrual Cycle)

HOW WE are born

GENE CLONING 

GENOME Sequencing

STEM CELLS

Genetically Modified Food

Gel Electrophoresis

Polymerase Chain Reaction 

Cell Division

Cell Structure and Function

Cell Organelles and Function

Glycolysis

Electron Transport System

DNA Replication

Trascription 

Translation (Protein Synthesis)

Tanscription and Translation

Practical manual of Genetic engineering

Practical manual of Genetic engineering/ Molecular Biology/ Recombinant DNA Technology

Download the practical manual

• This practical manual has some basic experiments for the beginners pursuing graduation in Biotechnology or Allied field. 
• Plz post your comments about any practical related doubts or clarification. or mail me at arvindarya@hotmail.com, catechize20@gmail.com

Have fun 

Transfer-Messenger RNA

Transfer-messenger RNA (abbreviated tmRNA, also known as 10Sa RNA and by its genetic name SsrA) is a bacterial RNA molecule with dual tRNA-like and messenger RNA-like properties. The tmRNA forms a ribonucleoprotein complex (tmRNP) together with Small Protein B (SmpB), Elongation Factor Tu (EF-Tu), and ribosomal protein S1. In trans-translation, tmRNA and its associated proteins bind to bacterial ribosomes which have stalled in the middle of protein biosynthesis, for example when reaching the end of a messenger RNA which has lost its stop codon. The tmRNA is remarkably versatile: it recycles the stalled ribosome, adds a proteolysis-inducing tag to the unfinished polypeptide, and facilitates the degradation of the aberrant messenger RNA. In the majority of bacteria these functions are carried out by standard one-piece tmRNAs. In other bacterial species, a permuted ssrA gene produces a two-piece tmRNA in which two separate RNA chains are joined by base-pairing.
E. coli contains a small RNA, encoded by the ssrA gene, is synthesized as a 457 nt precursor RNA that is processed by RNaseE to a mature 363 nt RNA. This RNA is also known as tmRNA or 10Sa RNA.
The ssrA RNA has a number of important properties:

• Its secondary and tertiary structure partially resembles that of tRNA
  
  
• It can be charged with alanine
  
  
• It can be used as an mRNA which codes for a 10 amino acid long oligopeptide: ANDENYALAA.
  

The mechanism of action of the ssrA RNA is shown in the following figure:
When a ribosome stalls, the ssrA RNA charged with alanine is brought to the A-site of the ribosome by the SsrB protein. Peptidyl transferase activity transfers the nascent polypeptide to the alanine attached to ssrA.
The mRNA template is also displaced by the ssrA RNA. Further protein synthesis now uses ssrA as a template and ten further amino acids (ANDENYALAA) are added to the C-terminal end of the polypeptide.
However, the final two amino acids that are added (AA) mark the new protein for proteolysis by the two proteases ClpAP and ClpXP.
Thus any proteins that are only partially synthesized by stalled ribosomes can be rapidly destroyed and turned over.

further reading...

The tmRNA system for translational surveillance and ribosome rescue

 Biochemistry3107 - Fall 1999

Transfer-messenger RNA From Wikipedia